Guillainbarre syndrome gbs is an acute polyneuropathy with a variable degree of weakness. The full text of this article is available in pdf format. Distinct clinical characteristics of pediatric guillainbarre syndrome. It is the leading cause of acute flaccid paralysis in developed countries, in which polio has been eradicated 2. Guillainbarre syndrome in children childrens hospital of philadelphia. Guillain barre syndrome gbs is classically defined as an. Guillainbarre syndrome fact sheet national institute of. Prospective health care data routinely collected for administrative purposes may represent a. Neurologic problems persist in up to 20 percent of patients with the disease, and onehalf of these patients are severely disabled. Guillainbarre syndrome gbs is an acute polyradiculoneuropathy characterized by progressive motor weakness of limbs and areflexia. The guillainbarre syndrome gbs is an acute immunemediated polyneuropathy considered as the most common causes of acute flaccid paralysis in healthy. Guillainbarre syndrome american academy of pediatrics.
It is characterized by abnormal muscle coordination with poor balance and clumsy walking, weakness or paralysis of the eye muscles, and absence of the tendon reflexes. Pediatric guillainbarre syndrome in a 30year nationwide. Gbs can cause muscle weakness, pain, and shortterm temporary paralysis of the muscles in the face chest, and leg and those used to swallow. Guillain barre syndrome gbs is an acute, immunemediated polyradiculoneuropathy with a wide range of clinical manifestation. Objective clinical characteristics of pediatric guillainbarre syndrome gbs have been extensively studied whereas scarcely been compared. Guillainbarre syndrome is a rare disorder that causes your immune system to attack your peripheral nervous system pns.
Diagnosis, treatment and prognosis of guillainbarre syndrome gbs. Guillain barre syndrome gbs is an acquired disorder of the peripheral nerves, described best as a polyradiculoneuropathy. The acute immunemediated polyneuropathies are classified under the eponym guillainbarre syndrome gbs, after the authors of early. Understand the management of the child with guillain barre syndrome. Guillain barre syndrome gbs is a shortterm but often lifethreatening disorder that affects the nerves in the body. Askep guillain barre syndrome pdf guillain barre syndrome gbs is a rare disorder of the peripheral nervous system. Guillainbarre syndrome is the most common and most severe acute paralytic neuropathy, with about 100 000 people developing the disorder every year worldwide. Prognosis of guillainbarre syndrome in children ncbi. Guillainbarre syndrome gbs is an acuteonset, monophasic, immunemedi ated polyneuropathy.
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